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The PathHunter Human LPA2 (EDG4) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure EDG4 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
BioChain provides FDA Standard Frozen Tissue Array which is designed in conformance with FDA guideline and meeting the requirements for IHC (Immunohistochemistry) and IVD (In vitro Diagnostic Devices) certification. This tissue array has two slides which contain 30 different normal tissue types and 3 donors per tissue type.
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Lysophosphatidic acid (LPA) a bioactive lipid produced by several cell types including postmitotic neurons and activated platelets is thought to be involved in various biological processes including brain development Three cognate G-protein coupled receptors encoded by lpa(1)/lp(A1)/Edg-2/Gpcr26 lpa(2)/lp(A2)/Edg-4 and lpa(3)/lp(A3)/Edg-7 mediate the cellular effects of LPA However many LPA-induced responses including phospholipase C activation Ca sup 2 /sup mobilization adenylyl cyclase activation proliferation JNK activation AKT activation and stress fiber formation were absent or severely reduced in embryonic fibroblasts derived from lpa(1)(-/-) lpa(2)(-/-) mice The lysophosphatidic acid receptor LPA2 or endothelial differentiation G-protein coupled receptor 4(EDG-4) is expressed most abundantly in testes and peripheral blood leukocytes It is reported to be a distinctive functional marker for ovarian carcinoma
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ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
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There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More